Disease Definition
Keratoconus is a clinical condition in which the normal shape of the cornea changes due to thinning and protrusion.
It is non-inflammatory and is usually bilateral (although non-cornea), typically affects about two thirds of the cornea and causes mild to severe forms of vision.
Deformation of the cornea is seen in the picture:
The incidence is variable and ranges from 50 to 230 cases per 100,000 people. It is seen in all races and has no sexual preference.
The incidence of 1-sided keratoconus is 2.4-2.0%.
The onset of aging is at the age of puberty, when the cornea begins to thinness and highlights (coming forward), similar to Figure 1. This causes irregular astigmatism and increased corneal curvature.
Typically, this process takes 10 to 20 years to gradually cease.
The rate of progression of the disease varies, and its severity varies in the course of disease progression from a low astigma that should only be monitored until it is very thin and the cornea is scarred, requiring corneal transplantation.
- Allagille Alajill syndrome
- Albinism
- angelman syndrome
- Biedet Bardet Syndrome
- Brittle Cornea syndrome
- Congenital rubella
- Crouzon Crocodile Syndrome
- Down Down Syndrome
- Donalds Ellerz Syndrome
- HyperIgE Syndrome
- Ichthyosis Ichthyosis
- Marfan Marfan syndrome
- Mitral valve prolapse
- Noonan syndrome
- neuropromatosis
- Osteogenic Imperfect
- Seducantum elastic psedo xanthoma elasticum
- Other Reiger syndrome
- Turner Syndrome
- Aniridia
- Initial iris atrophy
- Floppy eylid syndrome
- Corneal Fuchs Disease
- Granular corneal granular dystrophy
- Lattice Cortical Lattice, (RP) Retinitis Pigmentosa
- Preterm infant retinopathy (ROP)
- Vernal conjunctivitis (seasonal conjunctivitis)
